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Position Function Location Job description
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Protein Chemistry Scientist Discovery Shanghai ChinaJob descriptionJob description
- Antibody developability assessment is mandatory, including antibody’s structural characterization, including intact mass, sequence confirmation, PTM and Glycan profiling, stability characterization, including: SDS-PAGE, SEC, HIC, CE-SDS and iCIEF.
- Recombinant protein purification on AKTA or other high-throughput antibody purification system is required occasionally.
- Keep laboratory records and present data to the project team.
Job requirements- Ph.D. or M.Sc. in pharmaceutical analysis, protein chemistry, biology, biochemistry, structural biology or related fields.
- Protein QC experience including SEC/HIC/Glycan profiling/CE-SDS/iCIEF by using HPLC/UPLC/Maurice. Familiar with different chromatography methods to analyze protein is preferred.
- Experience in protein conformational and thermal stability analysis is a plus, Tm /Tagg/Tonset /KD detection.
If you are a like-minded person who seeks challenges and excitement, we invite you to join us. Please submit your CV and enquiries to joinus@elpiscience.com -
Translational Research Medicine Senior Scientist Discovery Shanghai ChinaJob descriptionJob description
- Design, plan and execute in vitro and ex vivo assays to provide translational data that bridges discovery thinking with clinical needs for our programs at various maturity states from target idea to screening and asset optimization prior to candidate selection.
- Identification of novel or most suitable biomarkers for patient selection or stratification as well as monitoring of pharmacodynamics in animal models and patients as needed for clinical studies.
- A team player mentality and interest in managing external CRO activities are required to connect with all internal partners and external collaborators to foster a productive culture and deliver results.
Job requirements- Master or PhD degree in biochemistry, cell biology, pharmacology or clinical sciences; candidates with immunology and/or oncology background are strongly preferred.
- Significant hands-on experience in assay development or biomarker development, 3D cultures systems or exosome biology.
- Extraordinary flexibility and ability to think independently but work collaboratively within a big multidisciplinary matrix team of a fast-growing biotechnology organization.
If you are a like-minded person who seeks challenges and excitement, we invite you to join us. Please submit your CV and enquiries to joinus@elpiscience.com -
Project Scientist Discovery Shanghai ChinaJob descriptionJob description
- Provide technically expertise to design, develop and perform hits finding for drug discovery.
- Provide scientific input into experimental design and data interpretation.
- Work in a close matrix team with other capabilities/disciplines to perform MoA studies.
Job requirements- Ph.D./Master’s degree in biochemistry, cell biology, pharmacology or other related field, immunology background preferred.
- Familiar with immunological assays such as M1/M2, T cell proliferation, ADCC, ADCP, and so on, is a plus.
- Ability to work independently as well as collaboratively within a multidisciplinary team.
If you are a like-minded person who seeks challenges and excitement, we invite you to join us. Please submit your CV and enquiries to joinus@elpiscience.com -
In Vivo Pharmacology Senior Scientist Discovery Shanghai ChinaJob descriptionJob description
- Lead by line function leader, to deliver an in vivo pharmacology strategy to support program needs; to deliver high quality in vivo pharmacology studies, data packages and study reports for assigned projects; to build in-house technical capabilities in a fast-paced work environment as necessary.
- To build strong collaborations with and external partners and CRO companies, and to be accountable for guiding CROs to deliver high quality studies.
Job requirements- Ph.D./Master/Bachelor’s degree in pharmacology or related fields; immunology and oncology background preferred but not mandatory.
- At least two years of proven in vivo pharmacology experience including CDX, PDX, GEMM, and humanized PBMC/CD34+ cell models. Solid training in cell culture, mouse handling, tumor inoculation, iv, ip, sc dosing, tumor measurements, humane sacrifice of animals and dissection of tumor and other tissues are mandatory. Additional expertise, e.g., ELISA, flow cytometry, histopathology, ‘omics approaches etc., are a plus.
- Highly motivated, independent thinking and highly collaborative with multidisciplinary matrix teams.
If you are a like-minded person who seeks challenges and excitement, we invite you to join us. Please submit your CV and enquiries to joinus@elpiscience.com -
Bispecific Antibody Assay Scientist Discovery Shanghai ChinaJob descriptionJob description
- Design, coordinate and conduct experimental procedures. Modify and adapt experimental protocols, techniques and procedures to specific project requirements.
- Perform in vitro functional assays for novel combinations and bispecific antibody proof of concept and mechanism of action (MOA) study.
- Study area will focus on immune-oncology field, especially in T cell biology, innate immunity (macrophage, NK cells), tumor microenvironment and cold tumor.
Job requirements- Ph.D. or master degree with 1+ year of working experience. Background in biochemistry, cell biology, oncology, immunology or related field.
- Experience/skills in cell based functional assays, especially in bispecific antibody related field such as CD3 based T cell killing assay, NK cell assay or macrophage-based phagocytosis and polarization assay.
- Excellent technical skill sets, especially for cell-based assay (cell culture, transient/stable transfection/transduction, reporter assay), and immunology assay (ELISA, FACS, MLR assay).
If you are a like-minded person who seeks challenges and excitement, we invite you to join us. Please submit your CV and enquiries to joinus@elpiscience.com -
Toxicologist Discovery Shanghai ChinaJob descriptionJob description
- Responsible for designing, coordinating and overseeing toxicology studies of company’s product portfolios.
- Coordinate with CROs and provide guidance and leadership in toxicology studies, and ensure the toxicology studies meet the guidelines of regulatory agencies of NMPA, FDA, EMEA and other agencies.
- Responsible for the toxicology sections of IND, BLA/NDA and other related documents for regulatory submissions.
Job requirements- Ph.D. in Toxicology, Pharmacology, Biology or related disciplines.
3+ years' toxicology study related experiences at a CRO or biotech companies. - 3+ years of experience as a study director/or equivalent in toxicology studies
If you are a like-minded person who seeks challenges and excitement, we invite you to join us. Please submit your CV and enquiries to joinus@elpiscience.com
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